Table 2. Sensitivities and specificities of different cut-off values for TGA in detecting celiac disease.
TGA: anti-transglutaminase antibody; PPV: positive predictive value; NPV: negative predictive value
TGA cut-off value | |||
>10 U/mL | >29.42 U/mL | >100 U/mL | |
Sensitivity, %, value (95% CI) | 100 (94.64–100) | 100 (94.64–100) | 71.64 (59.31–81.99) |
Specificity, %, value (95% CI) | 96.53 (92.99–98.6) | 99.50 (97.27–99.99) | 100 (98.19–100) |
PPV, %, value (95% CI) | 90.54 (82.21–95.2) | 98.53 (90.46–99.79) | 100 |
NPV, %, value (95% CI) | 100 | 100 | 91.40 (87.90–93.96) |