Skip to main content
. 2022 Jul 3;14(7):e26521. doi: 10.7759/cureus.26521

Table 4. TGA values in the diagnosis of celiac disease at different cut-off levels.

TGA: anti-transglutaminase antibody; PPV: positive predictive value

TGA cut-off value Sensitivity, % Specificity, % PPV, %
  Value 95% CI Value 95% CI Value 95% CI
21.74 U/mL 100% 94.64–100 99.0% 96.47–99.88 97.1% 89.40–99.25
29.42 U/mL 100% 94.64–100 99.5% 97.27–99.99 98.5% 90.46–99.79
39.69 U/mL 95.5% 87.47–99.07 100% 98.19–100 100%  
41.31 U/mL 92.5% 83.44–97.53 100% 98.19–100 100%  
TGA >10 and villous atrophy
29.42 U/mL 100% 94.40–100 98% 95.08–99.47 94.1% 85.84–97.69
36.1 U/mL 100% 94.40–100 98.5% 95.78–99.7 95.5% 87.40–98.50
39.69 U/mL 96.9% 89.16–99.62 99% 96.52–99.88 96.8% 88.64–99.19
41.31 U/mL 93.8% 84.76–98.27 99% 96.52–99.88 96.7% 88.29–99.17
52.7 U/mL 90.6% 80.70–96.48 100% 98.22–100 100%