Table 5.

Selected clinical findings of Hereditary Neuropathy with liability to Pressure Palsy (HNPP) patients reported in VAERS following Adenovirus Type4 and Type 7 Vaccine, Live, Oral, October 2011 through July 2018.

Case/ Year	Age (Yr) Sex	Recent History of Illness	Vaccines	Onset after Adenovirus vaccination (days)	Diminished DTR	CSF	EMG and NCS	Treatment	Genetic testing	Diagnosis
1 2016	20M	None	Adeno Hep A IIV IPV MCV4 Tdap Varicella	7	Normal	Not done	Acute demyelinating polyneuropathy on nerve conduction study	IVIG for presumed GBS	Positive for PMP22 gene deletion	HNPP
2 2016	17M	None	Hep B IIV Tdap MCV4 Tdap Adeno	8	√	Not done	Acute demyelinating polyneuropathy on nerve conduction study	6 day steroid course initially	Positive for PMP22 gene deletion	HNPP
3 2016	19F	URTI	Adeno Hep A IIV IPV MCV4 MMR Tdap Varicella	4	√	Not done	Acute demyelinating polyneuropathy on nerve conduction study	IVIG for presumed GBS	Positive for PMP22 gene deletion	HNPP

Abbreviations used in this table: Yr = year, DTR = deep tendon reflexes, CSF = cerebrospinal fluid, EMG and NCS = electromyogram and nerve conduction study, M = male, F = female, Adeno = adenovirus vaccine, Hep A = hepatitis A vaccine, IIV = inactivated influenza vaccine, IPV = inactivated poliovirus vaccine, MCV4 = meningococcal conjugate vaccine, Tdap = tetanus diphtheria attenuated pertussis vaccine, IVIG = intravenous immunoglobulin, GBS = Guillain Barré syndrome, PMP22 = peripheral myelin protein 22, HNPP = hereditary neuropathy with liability to pressure palsy, Hep B = hepatitis B vaccine, √ = diminished DTRs, URTI = upper respiratory tract infection, MMR = measles mumps and rubella vaccine.