Table 1.

Clinical and epidemiological features of patients with COVID-19 versus patients with H7N9 virus infection at admission

Variables	COVID-19-ARDS (n = 66)	COVID-19-non-ARDS (n = 34)	P1 value	H7N9-ARDS (n = 32)	H7N9-non-ARDS (n = 14)	P2 value	Pa value
Age (≥65 years)	39(59.1%)	13(38.2%)	0.048	16(50%)	2(14.3%)	0.011	0.395
Sex (male)	33(50%)	19(55.9%)	0.577	25(78.1%)	7(50%)	0.119	0.008
Clinical symptoms
Temperature >39.0 °C	2(3.0%)	0(0%)	0.547	24(75%)	14(100%)	0.102	<0.001
Fatigue	43 (65.2%)	17(50%)	0.143	24(75%)	10(71.4%)	1	0.326
Anorexia	25(37.9%)	4(11.8%)	0.006	15(46.9%)	5(35.7%)	0.482	0.395
Myalgia	10(15.2%)	4(11.8%)	0.874	8(25%)	3(21.4%)	1	0.238
Dry cough	47(71.2%)	24(70.6%)	0.948	6(18.8%)	5(35.7%)	0.387	<0.001
Expectoration	25(37.9%)	14(41.2%)	0.749	20(62.5%)	8(57.1%)	0.732	0.022
Dyspnea	49(74.2%)	22(64.7%)	0.319	29(90.6%)	8(57.1%)	0.026	0.059
Abdominal pain	7(10.6%)	3(8.8%)	1	0(0%)	0(0%)	/	0.135
Diarrhea	17(25.8%)	11(32.4%)	0.487	4(12.5%)	1(7.1%)	0.982	0.134
Nausea	3(4.5%)	3(8.8%)	0.683	3(9.4%)	0(0%)	0.543	0.627
Vomiting	3(4.5%)	2(5.8%)	1	3(9.4%)	0(0%)	0.543	0.627
Underlying disease
Hypertension	32(48.5%)	13(38.2%)	0.329	15(46.9%)	3(21.4%)	0.104	0.08
Diabetes	11(16.7%)	8(23.5%)	0.407	9(28.1%)	0(0%)	0.071	0.187
Chronic lung disease	7(10.6%)	1(2.9%)	0.342	5(15.6%)	0(%)	0.293	0.702
Chronic heart disease	10(15.2%)	3(8.8%)	0.564	1(3.1%)	0(0%)	1	0.153
Chronic renal disease	1(1.5%)	0(0%)	1	1(3.1%)	0(0%)	1	1
Chronic liver disease	1(1.5%)	0(0%)	1	2(6.3%)	0(0%)	1	0.248
Malignancies	4(6.1%)	1(2.9%)	0.846	1(3.1%)	0(0%)	1	0.897
Immunocompromised	1(1.5%)	1(2.9%)	1	1(3.1%)	0(0%)	1	0.549
Days from illness onset to admission	11.00 (5.75-16.00)	11.50 (9.75-15.25)	0.702	7.00 (5.00-9.75)	7.50 (5.00-9.00)	0.646	0.002

^aComparison between COVID-19-ARDS and H7N9-ARDS

ARDS: Acute respiratory distress syndrome.