Table 5.
Levels of lymphocyte subsets in HCWs with nonsevere and severe COVID-19.
| Categories | All (N = 534) | Nonsevere (N = 198) | Severe (N = 336) | P |
|---|---|---|---|---|
| B cells (%) | 9.90 (7.79-12.30) | 9.90 (7.85-12.08) | 9.90 (7.72-12.42) | 0.963 |
| Elevated | 12 (2.2%) | 5 (2.5%) | 7(2.1%) | 0.918 |
| Normala | 4.29-18.31 | 4.29-17.60 | 4.30-18.31 | |
| Decreased | 15 (2.8%) | 6 (3.0%) | 9 (2.7%) | |
| CD3+ T cells (%) | 70.67 (64.37-75.92) | 71.17 (65.15-76.40) | 70.04 (63.92-75.55) | 0.254 |
| Elevated | 7 (1.3%) | 0 (0.0%) | 7(2.1%) | 0.068 |
| Normala | 58.21-83.83 | 58.34-82.80 | 58.21-83.83 | |
| Decreased | 58 (10.9%) | 18 (9.1%) | 40 (11.9%) | |
| CD4+ T cells (%) | 35.58 (31.01-40.36) | 36.40 (31.49-40.10) | 35.02 (30.54-40.85) | 0.280 |
| Elevated | 11 (2.0%) | 3 (1.5%) | 8 (2.4%) | 0.423 |
| Normala | 25.40-51.33 | 25.59-51.33 | 25.40-50.41 | |
| Decreased | 26 (4.9%) | 7 (3.5%) | 19 (5.7%) | |
| CD4+/CD8+ cell ratio | 1.42 (1.14-1.82) | 1.42 (1.18-1.77) | 1.42 (1.09-1.86) | 0.746 |
| Elevated | 22 (4.1%) | 8 (4.0%) | 14 (4.2%) | 0.427 |
| Normala | 0.46-2.72 | 0.61-2.72 | 0.46-2.72 | |
| Decreased | 1 (0.2%) | 1 (0.5%) | 0 (0.0%) | |
| CD8+ T cells (%) | 25.20 (20.76-29.98) | 25.17 (21.13-29.72) | 23.35 (20.63-30.39) | 0.820 |
| Elevated | 24 (4.5%) | 10 (5.1%) | 14 (4.1%) | 0.793 |
| Normal | 14.24-38.48 | 14.24-38.48 | 14.41-38.32 | |
| Decreased | 19 (3.6%) | 6 (3.0%) | 13 (3.9%) | |
| NK cells (%) | 16.89 (12.01-22.75) | 16.07 (11.98-23.09) | 17.42 (12.01-22.58) | 0.668 |
| Elevated | 44 (8.2%) | 15 (7.6%) | 29 (8.6%) | 0.852 |
| Normala | 3.51-30.44 | 4.58-29.66 | 3.51-30.44 | |
| Decreased | 2 (0.4%) | 1 (0.5%) | 1 (0.3%) |
Data are presented as median (IQR) or n (%).
a
Data are shown as the normal ranges of the indicators.
Abbreviations: HCWs, healthcare workers; IQR, interquartile range
The continuous covariate between two groups was compared with Mann-Whitney U test. The comparison of categoric covariates between two groups was evaluated using chi-square test and Fisher's exact test.