Table 2:
Means and standard deviations of laboratory values by acute respiratory distress syndrome (ARDS) severity. Means were calculated using laboratory values during the same time PaO2/FiO2 was determined. ECMO patients were not included in this table.
| Measure | Mild ARDS (PaO2/FiO2 300– 200) |
Moderate ARDS (PaO2/FiO2 100–200) |
Severe ARDS (PaO2/FiO2 <100) |
|---|---|---|---|
| N, total patients | 1 | 14 | 31 |
| PaO2/FiO2a, (SD) | 263 | 147 (27.7) | 82 (14.2) |
| Aspartate Transaminase, U/L (SD) | 59 | 55 (86) | 255 (1864) |
| Alanine Aminotransferase, U/L (SD) | 64 | 42 (47) | 108 (621) |
| D-Dimer, ng/mL (SD) | 4641 | 8937 (16546) | 9744 (16996) |
| Hematocrit, % (SD) | 27 | 28 (5) | 28 (6) |
| Platelets, x109/L (SD) | 265 | 220 (127) | 192 (115) |
| White Blood Count, x103/mL (SD) | 11.9 | 13.1 (7.0) | 14.7 (8.3) |
| C-reactive protein, mg/L (SD) | 7.6 | 12.6 (10.2) | 15.2 (10.0) |
| Fibrinogen, mg/dL (SD) | 460 | 458 (245) | 417 (240) |
| Lactate, mmol/L (SD) | 1.92 | 1.63 (1.52) | 3.20 (4.19) |
| Lactate Dehydrogenase, U/L (SD) | 438 | 455 (290) | 407 (228) |
| pH, (SD) | 7.39 | 7.37 (0.08) | 7.33 (0.12) |
| INRb, (SD) | 1.20 | 1.27 (0.43) | 1.23 (0.36) |
| PTTc, seconds (SD) | 48.3 | 44.0 (20.9) | 45.0 (19.8) |
| Creatinine, mg/dL (SD) | 2.11 | 1.54 (1.59) | 1.62 (1.36) |
| von Willebrand Factor, µg/mL (SD) | 36.9 | 45.4 (20.5) | 47.4 (25.1) |
| A disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13, ng/mL (SD) | 459 | 332 (184) | 397 (169) |
| Plasminogen Activator Inhibitor-1, ng/mL (SD) | 31.8 | 33.1 (15.9) | 44.2 (14.9) |
| Tissue Factor Pathway Inhibitor, ng/mL (SD) | 408 | 444 (174) | 513 (251) |
| Microparticle-Bound Tissue Factor, pg/mL (SD) | 1.2 | 1.2 (1.0) | 1.8 (1.5) |
| Factor VIII activity, optical density at 650 nm (SD) | 1.41 | 1.32 (0.34) | 1.48 (0.27) |
| Anti-Factor Xa activity, IU/mL (SD) | 0.14 | 0.16 (0.09) | 0.17 (0.08) |
a
PaO2/FiO2: partial pressure of oxygen (PaO2) to fraction of inspired oxygen (FiO2)
b
INR: international normalized ratio
c
PTT: Partial thromboplastin time