Table 1.
Summary of Mouse Strains
| Genotype | Purpose | Reference | Source |
|---|---|---|---|
| Wild-type | Characterization of controls | (Simon et al., 2013) | Jax Stock # 000664 |
| CX3CR1CreER-iresGFP/+ | Differential fate-mapping of microglia and macrophages. | (Parkhurst, et al., 2013) | C. Parkhust and W.B. Gan, NYULMC |
| Rosa26stop-DsRed | Red reporter | (Luche, Weber, Nageswara Rao, Blum, & Fehling, 2007) | C. Parkhust and W.B. Gan, NYULMC |
| CCR2 −/− | Blocks monocyte recruitment into inflamed CNS | (Boring et al., 1997) | Jax Stock # 004999 |
| TNFα−/−/IL1−/−/C1q−/− | Deficient activation of a toxic astrocyte phenotype | (Lidelow et al., 2017) | Liddelow lab, NYULMC |
Wild type mice, and all alleles were expressed on the C57BL/6 background.