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. 2022 Jul 3;240:114572. doi: 10.1016/j.ejmech.2022.114572

Fig. 17.

Fig. 17

A: Chemical structure and production path of SARS-CoV-2 PLpro inhibitors compounds 7074; B: Removal of carbon-containing (R)-methyl group severely reduces the PLpro inhibitory activity in compound 75.