Fig. 28.
Chemical structure and anti-SARS-CoV-2 activity of chalcone amide-based lead compound GRL0617 and compounds 129–131 identified by HTS as the most active SARS-CoV-2 PLpro inhibitors, and subsequent optimized potent analogues 132–137 [53].
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.