Table 10.

Data showing the GAK inhibition and DENV inhibition of a series of isothiazolo [4,3-b] pyridines.

Compound No.	Heterocyclic Scaffolds	Kd	EC50	EC90	CC50
55		0.0089	1.844	8.05	17
56		0.97	5.72	>10	>10
57		0.25	0.18	0.56	2.09
58		0.089	0.82	1.76	>25
59		0.035	0.8416	3.92	4.14
60		0.052	4.03	>10	>10
61		0.018	0.47	1.34	6.32
62		0.011	0.70	2.15	>10