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Inhibition activity and cytotoxicity values of the most potent scaffolds.
| Compound No. | Heterocyclic Scaffolds | EC50 | CC50 | SI |
|---|---|---|---|---|
| 90 |  |
0.8 ± 0.2 | 18.1 ± 1.0 | 23 |
| 91 |  |
0.8 ± 0.2 | 17.3 ± 0.8 | 22 |
| 92 |  |
7.4 ± 1.0 | 40 ± 1.2 | 5 |
| 93 |  |
9.1 ± 1.0 | 30.2 ± 1.5 | 3 |
| 94 |  |
4.6 ± 0.9 | 25.1 ± 1.2 | 5 |
| 95 |  |
19.9 ± 1.3 | – | – |
