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. 2022 Jul 3;240:114576. doi: 10.1016/j.ejmech.2022.114576

Table 21.

Inhibition activity and cytotoxicity values of the few selected thiazole-based compounds in the virus reduction yield assay against DENV2.

Compound No. Heterocyclic Scaffolds EC50 (μM) CC50 (μM) SI
116 Image 124 7.00 ± 4.16 54.6 ± 38.8 8
117 Image 125 8.44 ± 2.02 86.8 ± 30.1 10
118 Image 126 3.79 ± 1.22 25.6 ± 11.9 7
119 Image 127 1.32 ± 0.41 125.0 ± 40.8 95