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Several N-substituted 1,2-benzoisothiazol-3(2H)-ones derivatives and their inhibition activity.
| Compound No. | Heterocyclic Scaffolds | %DENV Inhibition | IC50 (μM) |
|---|---|---|---|
| 120 |  |
72% | 41.80 ± 1.17 |
| 121 |  |
67% | 52.70 ± 3.23 |
| 122 |  |
92% | 2.56 ± 1.03 |
| 123 |  |
80% | 8.24 ± 1.16 |
| 124 |  |
89% | 6.66 ± 2.17 |
| 125 |  |
94% | 2.01 ± 0.98 |
| 126 |  |
94% | 5.28 ± 1.89 |
