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. 2022 Jul 3;240:114576. doi: 10.1016/j.ejmech.2022.114576

Table 25.

Inhibition activity of some selected conjugated thiazolidinone-thiazole scaffolds against DENV-2 NS5 RdRp polymerase.

Compound No. Heterocyclic Scaffolds IC50 (μM)
135 Image 143 2.3 ± 0.5
136 Image 144 2.1 ± 0.4
137 Image 145 5.5 ± 0.4
138 Image 146 5.8 ± 0.8
139 Image 147 7.2 ± 0.3