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Inhibition activity of some selected 2,1-benzothiazine 2,2-dioxide against DENV3 NS5 RdRp.
| Compound No. | Heterocyclic Scaffolds | IC50 (μM) |
|---|---|---|
| 140 |  |
0.6 ± 0.1 |
| 141 |  |
0.9 ± 0.1 |
| 142 |  |
2.6 ± 0.4 |
| 143 |  |
4.7 ± 0.7 |
| 144 |  |
4.7 ± 1.0 |
| 145 |  |
7.0 ± 0.7 |
| 146 |  |
7.0 ± 1.0 |
