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Inhibition activity of the most potent oxadiazole derivatives against the DENV1-4.
| Compound No. | Vero E6 CC50 (μM) | DENV-1 EC50 (μM) | DENV-2 EC50 (μM) | DENV-3 EC50 (μM) | DENV-4 EC50 (μM) |
|---|---|---|---|---|---|
| 147 | >100 | 2.0 | 2.7 | 3.7 | 3.0 |
| 149 | 30 | 5.9 | 4.7 | – | – |
| 150 | >100 | 6.9 | 12 | 9.8 | 10.0 |
| 151 | >100 | 2.5 | 2.6 | 3.0 | 3.0 |
