Table 33.

Comprehensive SAR of the reported O-heterocyclic scaffolds.

O-Heterocyclic Scaffold	SARs	Key Highlights	References
Coumarin		•Inhibits DENV2. •The existence of a cyclic 6-membered structure on the coumarin 114 is responsible for greater inhibition as compared to the acyclic structure on coumarin 115.	[175]