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Effect of 3′-substitution on the triazole molecular backbone for the inhibition of DENV.
| Compound No. | Heterocyclic Scaffolds | %Inhibition | %Cell Viability |
|---|---|---|---|
| 8 |  |
85% | 86% |
| 9 |  |
99% | 60% |
| 10 |  |
0% | 90% |
| 11 |  |
99% | 47% |
| 12 |  |
75% | 93% |
| 13 |  |
64% | 93% |
| 14 |  |
47% | 100% |
| 15 |  |
0% | 100% |
| 16 |  |
95% | 73% |
| 17 |  |
21% | 100% |
