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Inhibition activity and cytotoxicity values of pyrazine 2,3-dicarboxamide and phthalamide-based pyrazole scaffolds.
| Compound No. | Heterocyclic Scaffolds | EC50 (μM) | CC50 (μM) | SI |
|---|---|---|---|---|
| 20 |  |
26.5 | >116 | >4 |
| 21 |  |
0.5 | >117 | >235 |
| 22 |  |
2.2 | >120 | >55 |
| 23 |  |
3.4 | 24 | 7 |
| 24 |  |
0.5 | >117 | >235 |
| 25 |  |
29 | >117 | >4 |
| 26 |  |
>120 | >120 | 1 |
| 27 |  |
14.1 | >122 | >9 |
