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Data showing the inhibition activity and the cytotoxicity values of the imidazole-based nucleoside scaffolds.
| Compound No. | Heterocyclic Scaffolds | IC50 (μM) | CC50 (μM) | SI |
|---|---|---|---|---|
| 47 |  |
0.27 | 1.24 | 4.59 |
| 48 |  |
0.55 | 3.99 | 7.25 |
| 49 |  |
6.57 | >50 | >7.67 |
| 50 |  |
14.63 | >50 | >3.42 |
| 51 |  |
22.29 | >50 | >2.24 |
| 52 |  |
>20 | >50 | – |
| 53 | Ribavirin | 6.66 | 48.98 | 7.35 |
