TABLE 1.
Association of the Acidovorax abundances with clinicopathological characteristics of NSCLC patients in tumor tissues
| Characteristic | Total | Acidovorax of tumor tissue | p‐value* | |
|---|---|---|---|---|
| Positive (%) | Negative (%) | |||
| Gender | ||||
| Male | 33 | 14 (42%) | 19 (58%) | 0.760 |
| Female | 17 | 8 (47%) | 9 (53%) | |
| Age | ||||
| <65 years | 19 | 6 (32%) | 13 (68%) | 0.173 |
| ≥65 years | 31 | 16 (55%) | 15 (45%) | |
| Smoking status | ||||
| Never smoked | 16 | 6 (37%) | 10 (63%) | 0.535 |
| Current or former smoker | 34 | 16 (47%) | 18 (53%) | |
| Histological subtype | ||||
| Adenocarcinoma | 35 | 16 (46%) | 19 (54%) | 0.041 |
| Squamous cell carcinoma | 11 | 2 (18%) | 9 (82%) | |
| Others | 4 | 4 (100%) | 0 (0%) | |
| Pathological stage † | ||||
| I, II | 30 | 13 (43%) | 17 (57%) | 0.910 |
| III, IV | 20 | 9 (45%) | 11 (55%) | |
| COPD | ||||
| Absent | 33 | 11 (33%) | 22 (67%) | 0.040 |
| Present | 17 | 11 (65%) | 6 (35%) | |
| EGFR gene mutation/ALK fusion gene | ||||
| Wild‐type | 34 | 16 (47%) | 18 (53%) | 0.535 |
| Mutant | 16 | 6 (38%) | 10 (62%) | |
| Recurrence | ||||
| Absent | 20 | 5 (25%) | 15 (75%) | 0.046 |
| Present | 26 | 14 (54%) | 12 (46%) | |
| TP53 gene mutation | ||||
| Absent | 41 | 14 (34%) | 27 (66%) | 0.022 |
| Present | 6 | 5 (83%) | 1 (17%) | |
Abbreviations: AC, adenocarcinoma; NSCLC, non‐small cell lung cancer; SCC, squamous cell carcinoma.
*
Fisher's exact test. p‐values of <0.05 are shown in bold.
†
According to the International Union Against Cancer (UICC) TNM Classification of Malignant Tumors, seventh edition (2010).