Table 1. Represents clinical characteristics of the patients recruited in this study.
Variables | (A) Tissue cohort (n=115) | (B) Serum cohort (n=65) | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
Case (n=85) | Control (n=30) | Relative expression of miR-34a (2-ΔΔCT) | Relative expression of let-7f (2-ΔΔCT) | Relative expression of miR-31 (2-ΔΔCT) | Case (n=50) | Relative expression of miR-34a (2-ΔΔCT) | Relative expression of let-7f (2-ΔΔCT) | Relative expression of miR-31 (2-ΔΔCT) | ||
Age, No. (%) | ||||||||||
<45 | 26 (37.1) | 16 (53.3) | −6.39±3.66 | −5.29±3.60 | −5.87±2.54 | 14 (28.0) | −5.63±2.57 | −3.01±2.92 | −2.76±2.08 | |
≥45 | 44 (62.8) | 14 (46.6) | −6.30±3.91 | −5.40±4.85 | −6.65±3.63 | 36 (72.0) | −5.88±2.80 | −6.94±4.15 | −4.97±3.62 | |
p-value | ns | ns | ns | ns | <0.001 | ns | ||||
Histological type, No. (%) | ||||||||||
Mucinous | 14 (16.5) | - | −6.15±3.12 | −3.71±3.31 | −7.03±3.40 | 8 (22.8) | −4.88±1.28 | −7.05±4.77 | −3.71±3.25 | |
Serous | 50 (58.8) | - | −6.52±4.34 | −6.30±4.93 | −6.36±3.04 | 15 (42.8) | −6.74±2.80 | −6.35±4.65 | −4.28±3.64 | |
Clear cell | 10 (11.5) | - | −5.58±3.38 | −4.10±3.12 | −8.34±4.57 | 6 (17.1) | −5.32±2.82 | −5.71±3.88 | −7.38±1.86 | |
Endometrioid | 11 (12.9) | - | −6.36±2.42 | −5.03±4.34 | −4.28±2.18 | 6 (17.1) | −3.84±2.99 | −3.63±1.81 | −2.82±2.13 | |
Other | - | - | - | - | - | - | - | - | - | |
p-value | ns | <0.05 | <0.05 | <0.05 | <0.05 | <0.05 | ||||
Distant metastasis, No. (%) | ||||||||||
Absent | 40 (47.0) | - | −5.19±3.36 | −3.56±2.66 | −5.35±2.35 | 14 (40.0) | −4.42±1.66 | −5.55±3.88 | −3.00±3.08 | |
Present | 45 (52.9) | - | −7.22±3.89 | −7.11±5.14 | −7.40±3.76 | 21 (60.0) | −6.74±2.86 | −6.46±4.68 | −5.25±3.34 | |
p-value | <0.005 | <0.005 | <0.005 | <0.005 | ns | <0.05 | ||||
FIGO stage, No. (%) | ||||||||||
Stage I-II | 41 (48.2) | - | −5.19±3.36 | −3.56±2.66 | −5.35±2.35 | 20 (57.1) | −4.24±1.72 | −8.37±4.92 | −6.43±4.14 | |
Stage III-IV | 44 (51.7) | - | −7.22±3.89 | −7.11±5.14 | −7.40±3.76 | 15 (42.8) | −6.85±2.78 | −4.15±2.60 | −2.96±1.80 | |
p-value | <0.005 | <0.005 | <0.005 | <0.005 | <0.005 | 0.0071 | ||||
Menopause status, No. (%) | ||||||||||
Yes | 52 (61.1) | - | −7.25±4.17 | −5.89±5.07 | −7.22±3.64 | 22 (62.8) | −6.26±3.02 | −6.83±4.19 | −4.82±3.36 | |
No | 33 (38.8) | - | −4.87±2.63 | −4.52±3.30 | −5.11±2.26 | 13 (37.1) | −5.07±1.99 | −4.35±3.90 | −3.58±3.40 | |
p-value | <0.005 | ns | <0.05 | ns | <0.05 | ns | ||||
Serum CA125 (U/mL) | 184±329.1 | 33.8±61.4 | 172±352.4 |
ns, not significant.