Table 1. Clinical, microbiologic, and surgical data of six subjects with NTM-LD and two with PsA-LD.
Patient | Age (yr), sex | Past medical history | WBC and differential* (cells/L & %) | NTM species | Lung segment or lobe removed |
---|---|---|---|---|---|
A | 49F | PiMZ, GERD, esophageal dyskinesia, vitamin D deficiency, vitiligo | 5.9×109 | M. intracellulare & M. yongonense | Posterior segment of RUL |
P59L27M7E6 | |||||
B | 67F | Prior left apical lung segmentectomy, cardiomyopathy, emphysema, esophageal dyskinesia, GERD, hypertension, fibromuscular dysplasia, hypothyroidism, LBBB, SS-B Ab (+) | 11.4×109 | M. intracellulare | Completion left pneumo-nectomy |
P77L12M9E1 | |||||
C | 37F | Chronic sinusitis | 10×109 | Macrolide-resistant MAC | RUL |
P70L18M9E3 | |||||
D | 64F | Asthma, GERD, depression, rheumatic fever, osteoporosis, mitral valve prolapse, scoliosis, hearing loss | 5.8×109 | M. intracellulare | LLL |
P70L18M9E3 | |||||
E | 61F | Asthma, GERD, irritable bowel syndrome, depression, osteoporosis | 7.7×109 | MAC | Lingula |
P75L11M11 | |||||
F | 65F | GERD, hypothyroidism | 9.5×109 | MAC | RML |
P66L20M12E1 | |||||
G | 74F | Chronic P. aeruginosa lung infection, esophageal dyskinesia, GERD, hypothyroidism | 8.4×109 | No history of NTM | RML |
P75L11M11 | |||||
H | 63F | Chronic P. aeruginosa lung infection, allergic rhinitis, GERD, sicca syndrome (SS-A Ab +), hypothyroidism, sinusitis | 8.6×109 | No history of NTM | Lingula |
P70L18M10E3 | SS-LLL |
GERD, gastroesophageal reflux disease; LBBB, left bundle branch block; LLL, left lower lobe; PiMZ, protease inhibitor MZ phenotype; RML, right middle lobe; RUL, right upper lobe; SS, superior segment; WBC, white blood cell (normal WBC range [4–10×109/L].
*Normal neutrophil percent range (42%–78%) and normal lymphocyte percent range (13%–41%).