Table 5. The choice of PGD for childbearing among participants with initial intention to marry (n = 972).
Choice of PGD | Total | Males | Females | p-value* | |
---|---|---|---|---|---|
Among participants who want children even if BRCA+ (n = 511) | 0.107 | ||||
PGD | 416 (61.8) | 181 (58.2) | 135 (67.5) | ||
Natural pregnancy | 192 (37.6) | 128 (41.2) | 64 (32.0) | ||
Undetermined | 3 (0.6) | 2 (0.6) | 1 (0.5) | ||
Among participants who do not want children if BRCA+ (n = 461) | 0.532 | ||||
PGD | 248 (53.8) | 113 (55.4) | 135 (52.5) | ||
Still do not want children | 213 (46.2) | 91 (44.6) | 122 (47.5) | ||
Among participants who initially wanted children but do not want children if BRCA+ (n = 269) | 0.624 | ||||
PGD | 189 (70.3) | 89 (68.5) | 100 (71.9) | ||
Still do not want children | 80 (29.7) | 41 (31.5) | 39 (28.1) | ||
Among participants who initially did not want children and do not want children if BRCA+ (n = 192) | 0.739 | ||||
PGD | 59 (30.7) | 24 (32.4) | 35 (29.7) | ||
Still do not want children | 133 (69.3) | 50 (67.6) | 83 (70.3) |
BRCA+: participant or their partner hypothetically had BRCA mutation.
*χ2 test for differences between males and females.