Table 2.
Baseline characteristics
| Characteristic | All (n = 1834) |
No MAKE30 (n = 1315) |
MAKE30 (n = 519) |
p value |
|---|---|---|---|---|
| Age, years | 67 (56–75) | 66 (55–74) | 70 (60–77) | < 0.001 |
| Male sex | 1021 (55.7%) | 740 (56.3%) | 281 (54.1%) | 0.41 |
| Body weight on ICU admission, kga | 78 (66–90) | 78 (67–91) | 75 (64–88) | 0.005 |
| Baseline creatinine, µmol/l | 123 (81–189) | 119 (80–181) | 132 (84–214) | 0.001 |
| Baseline creatinine approach | 0.51 | |||
| Obtained from first creatinine level in ICU | 1814 (98.9%) | 1303 (99.1%) | 511 (98.5%) | |
| Obtained from pre-admission creatinine level | 5 (0.3%) | 3 (0.2%) | 2 (0.4%) | |
| Obtained from estimated creatinine level | 15 (0.8%) | 9 (0.7%) | 6 (1.2%) | |
| Chronic liver disease | 152 (8.3%) | 84 (6.4%) | 68 (13.1%) | < 0.001 |
| Chronic cardiac disease | 307 (16.7%) | 203 (15.4%) | 104 (20.0%) | 0.017 |
| Chronic respiratory disease | 205 (11.2%) | 138 (10.5%) | 67 (12.9%) | 0.14 |
| Immune deficiency | 596 (32.5%) | 382 (29.0%) | 214 (41.2%) | < 0.001 |
| Location before ICU admission | < 0.001 | |||
| Other ICU | 83 (4.5%) | 67 (5.1%) | 16 (3.1%) | |
| Emergency department | 511 (27.9%) | 370 (28.1%) | 141 (27.2%) | |
| Recovery | 85 (4.6%) | 77 (5.9%) | 8 (1.5%) | |
| Operating room | 202 (11.0%) | 151 (11.5%) | 51 (9.8%) | |
| High dependency unit | 82 (4.5%) | 50 (3.8%) | 32 (6.2%)32 (6.2%) | |
| Ward | 871 (47.5%) | 600 (45.6%) | 271 (52.2%) | |
| Hospital | 0.039 | |||
| A | 552 (30.1%) | 409 (31.1%) | 143 (27.6%) | |
| B | 511 (27.9%) | 345 (26.2%) | 166 (32.0%) | |
| C | 770 (42.0%) | 561 (42.7%) | 209 (40.3%) | |
Data are n (%) or median (IQR)
MAKE30 major adverse kidney events within 30 days; ICU intensive care unit
aData available for 1289 (98%) patients in the No MAKE30 group and 509 (98%) patients in the MAKE30 group