Table 4.
Type and volume of administered fluids and urine output during the first 2 days in ICU
| Fluid type | No MAKE30 (n = 1315) |
MAKE30 (n = 519) |
||||
|---|---|---|---|---|---|---|
| No. of patientsa | Median (IQR) volume (ml)b | % of total fluid volumec | No. of patientsa | Median (IQR) volume (ml)b | % of total fluid volumec | |
| Total fluid input | 1315 | 8395 (6233–11,130) | 100 | 519 | 8559 (6245–11,531) | 100 |
| Resuscitation fluids | ||||||
| Ringer’s solution | 1235 | 3500 (2000–5357) | 41.7 | 481 | 3460 (2000–5670) | 41.0 |
| Albumin 40 or 50 g/l | 359 | 500 (481–1000) | 2.6 | 139 | 750 (490–1289) | 2.8 |
| Albumin 200 g/l | 498 | 200 (100 – 348) | 1.2 | 240 | 200 (100–400) | 1.5 |
| Hydroxyethyl starch | 212 | 963 (500–1014) | 1.8 | 77 | 1000 (500–1461) | 1.7 |
| Dextran | 111 | 600 (500–1000) | 0.8 | 28 | 733 (500–1000) | 0.6 |
| Gelofusine | 117 | 1500 (500–2000) | 1.4 | 30 | 1000 (500–1500) | 0.8 |
| Proportion of total fluid input from resuscitation fluids | 49.5 | Proportion of total fluid input from resuscitation fluids | 48.4 | |||
| Non resuscitation fluids | ||||||
| 0.9% saline | 1099 | 432 (152–921) | 6.9 | 451 | 506 (201–1178) | 9.2 |
| Glucose 25–200 g/l | 1283 | 2106 (1428–2891) | 24.3 | 509 | 2082 (1316–2954) | 23.6 |
| Glucose 300–500 g/l | 6 | 25 (20–40) | < 0.1 | 9 | 30 (20–90) | < 0.1 |
| Red blood cells | 458 | 500 (250–750) | 2.6 | 197 | 500 (250–750) | 2.8 |
| Plasma | 342 | 1000 (500–1750) | 4.3 | 147 | 750 (500–1500) | 3.9 |
| Platelets | 123 | 600 (300–650) | 0.6 | 100 | 600 (300–900) | 1.5 |
| Parenteral nutrition | 909 | 182 (12–1096) | 5.2 | 353 | 112 (11.8–1239) | 5.3 |
| Enteral (oral or nasogastric) fluids | 435 | 710 (325–1300) | 3.5 | 125 | 425 (200–800) | 1.9 |
| Enteral nutrition (IQR) | 345 | 326 (163–566) | 1.4 | 136 | 295 (171–495) | 1.4 |
| Electrolyte solutions | 1215 | 78 (36–143) | 1.2 | 474 | 94 (39–199) | 1.6 |
| Other fluids | 109 | 100 (40–280) | 0.3 | 64 | 169 (50–462) | 0.4 |
| Proportion of total fluid input from non-resuscitation fluids | 50.5 | Proportion of total fluid input from non-resuscitation fluids | 51.6 | |||
| Total urine output | 1305 | 4215 (2821–6098) | 511 | 3081 (1580–4787) | ||
aTotal number of patients who received the fluid type presented on each row
bMedian (IQR) delivered volume of each fluid (among those who received the specific fluid type)
cProportion of total fluid intake in the No MAKE30 group and MAKE30 group, respectively