Fig. 8.

Summary of the pathologies highlighted in this review, proportion of females in the affected population, and the current association with menopause. In cardiovascular disease (CVD), osteoporosis, and osteoarthritis (OA), menopause alone is considered a sex-specific factor and early menopause further increases the risk of developing these pathologies. To date, menopause has not been determined to be associated with developing glaucoma and it is not a consideration when monitoring glaucoma progression or when deciding on treatment. However, we highlight the similarities of glaucoma to these other pathologies and propose that menopause is potentially a novel sex-specific risk factor for developing glaucoma in females