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. 2022 Jun 20;9:875244. doi: 10.3389/fcvm.2022.875244

Table 3.

Hazard ratios for events per one unit increase in uFABP3/uCr.

Unadjusted P Adjusted P
HR (95% CI) HR (95% CI)
MALE 1.24 (1.10–1.40) 0.001 1.28 (1.16–1.41) 0.001
Vascular intervention 1.15 (1.02–1.28) 0.031 1.13 (1.02–1.26) 0.034
Major amputation 1.19 (0.92–1.55) 0.19 1.19 (0.81–1.76) 0.32
Worsening PAD (drop in ABI ≥ 0.15) 1.15 (1.04–1.27) 0.009 1.16 (1.02–1.27) 0.021

MALE, major adverse limb event: composite of vascular intervention and major amputation; PAD, peripheral artery disease; ABI, ankle brachial index.

Adjusted for age, sex, hypertension, dyslipidemia, diabetes, smoking, coronary artery disease, congestive heart failure, medications (statins, ACE-I/ARB, beta blocker, diuretic, ASA, antiplatelets other than ASA, and low-dose rivaroxaban), and serum creatinine. Bold values represent statistically significant values (p < 0.05).