Table 2.

Multivariable analysis on independent risk factors for in-hospital mortality in the whole study population

	ORs (95%CI)	P value
Haematological malignancy	4.76 (2.4–9.4)	< 0.001
Thrombocytopenia at hospital admission1	3.03 (1.6–5.6)	< 0.001
Neutropenia at hospital admission2	31.1 (3.86–250.7)	0.001
Low albumin at hospital admission3	3.1 (2.1–6.6)	0.001
Days from admission to respiratory worsening* (> 10d)	3.3 (2–12.4)	0.002
Corticosteroids treatment	3.65 (1.49–8.96)	0.004
Prior (30-d) infection	57.7 (3.2–1014.4)	0.006
PO2/FiO2 at respiratory worsening* (< 250)	2.2 (1.3–10.4)	0.022

¹Thrombocytopenia was defined as platelets count < 150 × 10˄9/L; ²Neutropenia was defined as polymorphonuclear leukocytes count < 500 × 10˄9/L; ³level of serum albumin < 3.5 g/dl. *respiratory worsening was defined as: i) the need of supplementary oxygen therapy or ii) the need of increasing oxygen therapy supplementation in a patient with SARS-CoV2 infection for reasons directly related to the infection. A careful evaluation of causes of supplementary oxygen therapy for reasons other than SARS-CoV2 infection (i.e. cardiac failure, bacterial superinfections) was performed. In the case of doubt, a panel discussion was performed