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. 2022 Jun 20;9:924579. doi: 10.3389/fmed.2022.924579

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Copyright © 2022 Shi, Xiang, Feng, Yang, Li, Fang, Xu, Qi, Shen, Tang, Shen, Wang, Xu and Rao.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Clustering analyses of the differentially methylated mRNAs through Gene Ontology (GO) function and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway. (A) Enrichment of the differentially methylated mRNAs in GO categories such as biological process (BP), cellular component (CC), and molecular function (MF). (B,C) KEGG pathway involvement of differentially m⁶A mRNAs in patients with megaureter (M group) compared with vesicoureteral reflux (VUR, V group). (D) Enrichment of the differentially expressed mRNAs in GO categories such as BP, CC and MF. (E,F) KEGG pathway involvement of differentially expressed mRNAs in patients with the M group compared with the V group.