Table 3.
Linear mixed model fixed effects (Type-III Test).
| Fixed effect | F -value (DF = 35) | P -value |
|---|---|---|
| Anxiety (GAD-7) | ||
| CM | 0.13 | 0.723 |
| Sequence | 0.31 | 0.582 |
| Period | 0.04 | 0.851 |
| GAD Category | 13.59 | <0.001 |
| CM*GAD Category | 4.70 | 0.016 |
| PTSD (PCL-C) | ||
| CM | 0.04 | 0.840 |
| Sequence | 1.29 | 0.263 |
| Period | 1.91 | 0.176 |
| PCL-C Category | 5.46 | 0.009 |
| CM*PCL-C Category | 0.98 | 0.387 |
| Depression (CES-D) | ||
| CM | 0.02 | 0.887 |
| Sequence | 0.01 | 0.939 |
| Period | 0.67 | 0.420 |
| CES-D Category | 2.12 | 0.136 |
| CM*CES-D Category | 0.18 | 0.838 |
CM, Challenge Materials (0, placebo, 1, MSG). Sequence: 1, MSG/Placebo, 2, Placebo/MSG. Period: Challenge Week 1 v. Challenge Week 2. Bold, significant at the Bonferroni corrected p-value of 0.016.
*
indicates interaction.