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. 2020 Sep 25;29(4):212–216. doi: 10.1136/ejhpharm-2020-002340

Table 1.

Piperacillin/tazobactam content during storage in FOLFusor LV10 (Baxter) elastomeric devices as determined by stability indicating HPLC assay

Timepoint 90 mg/mL* 25 mg/mL†
PIP+TAZ, % remaining 95% CI (%) PIP+TAZ, % remaining 95% CI (%)
Day 0 100.0
(94.1±0.4 mg/mL)
99.6 to 100.4 100
(27.1±0.2 mg/mL)
99.1 to 100.9
Day 7 101.3 100.8 to 101.8 101.5 101.2 to 101.8
Day 10 99.7 99.5 to 99.9 100.3 99.9 to 100.7
Day 13 98.7 98.3 to 99.1 99.7 99.4 to 100.1
Day 13+1 98.0 97.8 to 98.2 100.9 100.3 to 101.5

*90 mg/ml total drug concentration: 80 mg piperacillin/10 mg tazobactam.

†25 mg/ml total drug concentration: 22 mg piperacillin/3 mg tazobactam.

PIP, piperacillin; TAZ, tazobactam.