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. 2022 Jun 10;26:141–157. doi: 10.1016/j.omto.2022.06.005

Figure 3.

Figure 3

RNA-seq analysis of mouse BLCA cell lines treated with 100 U rIFNα or LV-IFNα

(A–F) Heatmaps of significant genes (FDR cutoff 0.05 and fold change of 2) between 100 U IFNα and CTRL samples for BBN975 (A), MB49 (B), and UPPL1541 (C) and between LV-IFNα and LV-Ctrl samples for BBN975 (D), MB49 (E), and UPPL1541 (F). (G and H) Venn diagrams show significantly altered genes (FDR cutoff 0.05 and fold change of 1.5) common or unique to all the three cell lines after treatment with LV-IFNα and rIFNα. (I and J) GSEA shows enrichment of interferon alpha response pathway in MB49 cells treated with LV-IFNα and rIFNα.