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. 2022 Jun 20;12:903570. doi: 10.3389/fcimb.2022.903570

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Copyright © 2022 Rahman, Islam, -Or-Rashid, Mamun, Rahaman, Islam, Meem, Sutradhar, Mitra, Mimi, Emran, Fatimawali, Idroes, Tallei, Ahmed and Cavalu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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This is a diagram of cardiovascular risk and related to inflammation, the disorder of lipid metabolizing, diabetes relation with gut microbial disease. This gut microbiota reacts with the immune system of the animal or human body so that it can take control of the function of the gut barrier. A porous barrier influences the uprising of the flux of pro-inflammatory microorganisms (bacteria) into systemic circulation, thus the situation causes low-level inflammation through TLR activation (Xu et al., 2020).