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. 2022 Jun 20;13:921612. doi: 10.3389/fphar.2022.921612

TABLE 2.

Prevalence of pain and itch in diabetes in different areas, assessment methods in different studies.

Patients and area Number of diabetic patients Prevalence (%) Methods Reference
Pain
Patients with diabetes in northwest England n = 15,692 21 Questionnaire (NSS and NDS) Abbott et al. (2011)
Patients with diabetes in France nationwide n = 766 20.3 Questionnaire (DN4 and MNSI), monofilament test Bouhassira et al. (2013)
Patients with diabetes in United Kingdom n = 350 16.2 Questionnaire (VAS and McGill Pain) and examination Daousi et al. (2004)
Patients with diabetes in Italy n = 816 13 Clinical examination and diagnostic tests Truini et al. (2018)
Patients with T2DM in Denmark n = 5,114 10 Questionnaire (DN4 and MNSIq) Gylfadottir et al. (2020)
Itch
 Patients with diabetes in the United Kingdom n = 300 18.4 Interviewed and clinical examination Neilly et al. (1986)
 Diabetic outpatients in Japan n = 2,656 26.3 Questionnaire Yamaoka et al. (2010)
 Patients with T2DM in Taiwan, China n = 385 27.5 Questionnaire Ko et al. (2013)
 Children with T1DM in Poland n = 100 22 NRS and Questionnaire (4IIQ) Stefaniak et al. (2020)
 Patients with T2DM in Poland n = 109 35.8 NRS and Questionnaire (4IIQ) Stefaniak et al. (2021b)

DN4, Diabetic Neuropathy 4; NDS, neuropathy disability score; NSS, neuropathy symptom score; MNSI, Michigan Neuropathy Screening Instrument; VAS, visual analog scale; 4IIQ, Four-item Itch Questionnaire; NRS, numerical rating scale.