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. 2022 Jun 20;13:896645. doi: 10.3389/fimmu.2022.896645

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Copyright © 2022 Yao, Zhang, Niu, Yan, Tong, Zou, Li and Yang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Association between the hub genes and immune infiltration. (A) In GSE120642, the level of neutrophil infiltration was significantly associated withhub genes in PAD samples. Red: positive correlation; blue: negative correlation. (B) Detailed correlation results of hub genes and neutrophil infiltration in GSE120642. (C) In GSE111889, S100A8, S100A9, S100A12 and CXCR2 were shown to positivelycorrelate with most cell types except for activated B cells, plasmacytoid dendritic cells,CD56dim natural killer cells, CD56 bright natural killer cells and Type 17 T helper cells.Red: positive correlation; blue: negative correlation. (D) Detailed correlation results of hubgenes and neutrophil infiltration in GSE111889. PAD: peripheral artery disease. CD: Crohn's disease.