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Evodiamine suppressed the production of the inflammatory factors induced by IL-1β. (A,B,D) Expression of PGE2, TNF-α, and IL-6 was detected by ELISA. (C) Nitric oxide (NO) concentrations were assessed by Griess reaction. The data were expressed as mean ± SD. Significant differences between different groups are indicated as ##p < 0.01, vs. control group; ∗∗ p < 0.01, vs. IL-1β alone stimulation group, n = 3.
