Table 2.
PDCD4 expression in different subtypes of breast cancer.
| Cell line/Tissue Name | Subtype | Technique | Up/Down-regulation | Ref No. |
|---|---|---|---|---|
| Pregnancy-associated breast cancer | N/A | RT-PCR/IHC | Downregulate | 7 |
| IDC | N/A | IHC | Upregulate in cytoplasma and Downregulate in nucleus | 8 |
| LET-R / LTEDaro | LuminalA | RT-PCR/IHC | Downregulate | 9 |
| HER2aro | Her2 (+) | RT-PCR/IHC | Downregulate | 9 |
| DCIS/IDC | N/A | IHC | Downregulate in IDC but slightly decreased in DCIS | 29 |
| ER(+) breast cancer tissure | N/A | Reverse phase protein arrays | Downregulation was associated with node positivity | 31 |
| MDA-MB-231 | TNBC | RT-PCR/IHC | Downregulation | 51, 52 |
| HCC1937 | TNBC | RT-PCR | Downregulation | 59 |
| MDA-MB-468 | TNBC | RT-PCR | Downregulation | 59 |
| T47D | LuminalA | Western Blot | Downregulation | 25 |