Fig. 3.

Abnormal functional connectivity from ventrolateral thalamus to the inferior motor cortex in Rolandic epilepsy. (A) The inferior Rolandic motor cortex and ventrolateral (VL) thalamus (blue) were used as seed and target ROIs in each analysis. (B) Control children have no evidence of a relationship between functional connectivity from the VL th alamus to the inferior Rolandic motor cortex with age (p = 0.9). In contrast, children with active Rolandic epilepsy have increased functional connectivity between the VL thalamus and the inferior motor cortex with age (p = 0.022, effect size = 0.095). Similar to controls, children with resolved Rolandic epilepsy have no evidence of a relationship between functional connectivity from the VL thalamus to the inferior Rolandic motor cortex with age (p = 0.4).