Fig. 4.

Abnormal structural connectivity from ventrolateral thalamus to the inferior motor cortex in Rolandic epilepsy. (A) The inferior Rolandic motor cortex and ventrolateral (VL) thalamus (blue) were used as seed and target ROIs in each analysis. (B) Control children have decreased structural connectivity from the VL thalamus to the inferior Rolandic motor cortex with age (p = 0.022, β = -0.034). In contrast, children with active Rolandic epilepsy (red) have no relationship between structural connectivity from the inferior motor cortex to the VL thalamus and with age (p = 0.4). Opposite to controls, children with resolve Rolandic epilepsy (blue) have increase structural connectivity from the inferior Rolandic motor cortex to the VL thalamus with age (p = 0.025, β = 0.065).