Table 1.
Results of Logistic Regression Analysis for Age, Sex, CD4 Cell Count, Prior Tuberculosis, and Cryptococcal Antigenemia
| Variable parameters | n | CrAg Positive, % (n) | Unadjusted OR (95% CI) | P | Adjusted ORa (95% CI) | P |
|---|---|---|---|---|---|---|
| Age | ||||||
| <39 | 99 | 35.3 (35) | Base | Base | ||
| ≥39 | 102 | 31.4 (32) | 0.84 (.46–1.50) | .55 | 0.88 (.47–1.66) | .71 |
| Sex | ||||||
| Male | 102 | 29.4 (30) | Base | Base | ||
| Female | 99 | 37.4 (37) | 1.43 (.79–2.58) | .23 | 1.42 (.76–2.68) | .27 |
| CD4 (<50) | ||||||
| ≥50 | 66 | 18.2 (12) | Base | Base | ||
| <50 | 135 | 40.7 (55) | 3.09 (1.52–6.31) | .002 | 3.37 (1.60–7.11) | .001 |
| ART Statusb | ||||||
| Naive/defaulted | 172 | 29.7 (51) | Base | Base | ||
| On ART | 29 | 55.2 (16) | 2.92 (1.31–6.51) | .009 | 2.58 (1.09–6.09) | .03 |
| Prior TB | ||||||
| No prior TB | 172 | 20.2 (52) | Base | Base | ||
| Prior TB | 29 | 51.7 (15) | 2.47 (1.11–5.49) | .03 | 2.72 (1.13–6.52) | .03 |
Abbreviations: ART, antiretroviral therapy; CI, confidence interval; CrAg, cryptococcal antigen; OR, odds ratio; TB, tuberculosis.
a
All variables adjusted for age, sex, CD4 count, ART status, and prior TB. There was no association between age and CrAg status if age was included as a categorical or continuous variable.
b
ART status was categorized as naïve or defaulted if they had not taken any ART in the past 3 months.