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. 2022 Jan 7;122(6):998–1005. doi: 10.1055/s-0041-1740180

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The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. ( https://creativecommons.org/licenses/by-nc-nd/4.0/ )

This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited.

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Fig. 1 — Antifactor Xa activity at baseline and after administration of andexanet. ( A ) Patients on edoxaban with baseline antifactor Xa activity ≥40 ng/mL. ( B ) Patients on edoxaban with baseline antifactor Xa activity ≥75 ng/mL. The median antifactor Xa activity for each time point is marked as a horizontal line within the box. The bottom and top of the box denote the 25th and 75th percentiles, respectively. The lower and upper whiskers indicate the 10th and 90th percentiles, respectively. CI, confidence interval; N , number of patients with data.