KEY RESOURCES TABLE

REAGENT or RESOURCE	SOURCE	IDENTIFIER
Chemicals, peptides, and recombinant proteins
[U-13C]-malate	Cambridge Isotope Labs	Cat# CLM-8065
[U-13C]-succinate	Cambridge Isotope Labs	Cat# CLM-1571
Oligomycin	Caymen Chemical	Cat# 11342
Cyclosporine A	Caymen Chemical	Cat# 12088
S1QEL	Millipore Sigma	Cat# SML1948
S3QEL	Millipore Sigma	Cat# SML1554
n-propyl gallate	Millipore Sigma	Cat# P3130
Mito-tempo	Millipore Sigma	Cat# SML0737
Rotenone	Millipore Sigma	Cat# R8875
Antimycin A	Millipore Sigma	Cat# A8674
Amplex Red	Thermo-Fisher	Cat# A22189
Critical commercial assays
ATP/ADP Assay	Millipore Sigma	Cat# MAK135
GSH-glo Assay	Promega	Cat# V6911
CyQuant™ Cytotoxicity Assay	Thermo Fisher	Cat# C20300
BCA protein concentration assay	Thermo Fisher	Cat# 23225
Experimental models: Organisms/strains
C57BL6/J mice	The Jackson Laboratory	RRID: IMSR_JAX:000664
Software and algorithms
MSD Chemstation E.02.01.1177	Agilent Technologies	https://www.agilent.com/
IsoCor, v1.0	Millard et al., 2012	https://isocor.readthedocs.io/en/latest/index.html#
DatLab V7.3.0.3	Oroboros Instruments	https://www.oroboros.at/
Prism V9.3.1	Graphpad Software	https://www.graphpad.com/; RRID:SCR_002798