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. 2022 May 20;41(13):e109755. doi: 10.15252/embj.2021109755

Figure EV1. Sequence alignment among ClpPs.

Figure EV1

The UniProt IDs for the ClpP sequences are Bacillus subtilis ClpP (BsClpP) P80244, Neisseria meningitidis ClpP (NmClpP) Q9JZ38, Mycobacterium tuberculosis ClpP1 (MtuClpP1) P9WPC5, Mycobacterium tuberculosis ClpP2 (MtuClpP2) P9WPC3, and Staphylococcus aureus ClpP (SaClpP) Q2G036. Secondary structure elements are indicated (α‐helices ‐ coil; β‐strands ‐ arrow) and labeled above the sequence. Filled blue circles indicate the catalytic triad (S97‐H122‐D171), and the flexible handle region is marked with a black dashed box. His145 in NmClpP and its equivalent residues are highlighted in yellow. Identical residues are shaded in red, and highly conserved residues are marked in blue boxes. The sequence number for B. subtilis ClpP is indicated above the sequence.