Fig. 6.

DRP1 potentiates glycolysis in HNC cell that is required for MMP12. (A) The correlation between DRP1 and glycolytic molecules was assessed from the GEPIA database (n = 519). (B,C) Glucose consumption and lactate production were measured in siDRP1‐SAS and ‐HSC‐3 cells transfected with MMP12 or vector alone. (D) The transcriptional levels of glycolytic molecules were examined by QPCR in siDRP1‐SAS and ‐HSC‐3 cells transfected with MMP12 or vector alone. All data are presented as mean  ±  SD of three independent experiments. Significance calculated using t‐test. * P < 0.05, ** P < 0.01, *** P < 0.001.