Table 2.
Association between DRP1 expression and clinicopathological parameters in 92 surgery patients with HNSCC.
| Parameters | DRP1 expression | P‐value | |||
|---|---|---|---|---|---|
| All case | Low | High | |||
| n (%) | n (%) | n (%) | |||
| Age, years | ≤60 | 64 (69.6) | 32 (65.3) | 32 (74.4) | 0.343 |
| >60 | 28 (30.4) | 17 (34.7) | 11 (25.6) | ||
| Gender | Male | 86 (93.5) | 47 (95.9) | 39 (90.7) | 0.413 a |
| Female | 6 (6.5) | 2 (4.1) | 4 (9.3) | ||
| Cancer site | Oral | 65 (70.6) | 34 (69.4) | 31 (72.1) | 0.671 a |
| Oropharynx | 18 (19.6) | 11 (22.4) | 7 (16.3) | ||
| Hypopharynx and larynx | 9 (9.8) | 4 (8.2) | 5 (11.6) | ||
| pT status | T1–T2 | 55 (60.4) | 33 (67.3) | 22 (52.4) | 0.146 |
| T3–T4 | 36 (39.6) | 16 (32.7) | 20 (47.6) | ||
| pN status | N0 | 51 (55.4) | 32 (65.3) | 19 (44.2) | 0.042* |
| N1–N3 | 41 (44.6) | 17 (34.7) | 24 (55.8) | ||
| Clinical stage | I–II | 33 (35.9) | 22 (44.9) | 11 (25.6) | 0.05* |
| III–IV | 59 (64.1) | 27 (55.1) | 32 (74.4) | ||
| Adjuvant Tx | No | 40 (43.5) | 25 (51.0) | 15 (34.9) | 0.119 |
| Yes | 52 (56.5) | 24 (49.0) | 28 (65.1) | ||
a
P‐value for Fisher’s exact test. *Significant: P ≤ 0.05.