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. 2022 Jul 1;12(7):e060425. doi: 10.1136/bmjopen-2021-060425

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© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

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Tree diagram detailing the characteristics of spontaneous reports of myocarditis and pericarditis on the Vaccine Adverse Event Reporting System (VAERS) database following COVID-19 messenger RNA (mRNA) vaccines in immunocompromised individuals. Reports of myocarditis, pericarditis or myopericarditis were searched in the VAERS database following COVID-19 mRNA vaccines, either Moderna or Pfizer BioNTech. The resultant reports were further assessed for individuals that were likely to be immunocompromised based on the following search terms (transplant, tacrolimus, mycophenolate mofetil, methotrexate, prednisolone, ciclosporin). Transplant recipients were assessed separately to immunocompromised individuals that received medication, independent of disease setting. *Unspecified category, †cancer defined by use of cancer-approved medicines.