Table 1.
Basic patient characteristics and results of hormonal testing in women with FHA and healthy control women
| FHA (n = 64) | Controls (n = 32) | p | |
|---|---|---|---|
| Underweight < 18.5 kg/m2 a,b | 12 (18.8%) | - | - |
| weight loss > 10kga,b | 16 (25.0%) | - | - |
| Eating disordera,b | 19 (29.7%) | - | - |
| High level of exercisea,b | 26 (40.6%) | - | - |
| History of emotionally stressful eventsa,b | 15 (23.4%) | - | - |
| Age (years)c | 26 (21;29) | 26 (23;28) | 0.551 |
| BMI (kg/m2)c | 20.0 (18.6;22.4) | 21.5 (19.6;23.6) | 0.064 |
| TSH (IU/mL)c | 1.67 (1.15;2.16) | 1.41 (1.05;1.93) | 0.186 |
| FSH (mIU/mL)c | 4.5 (3.2;6.2) | 5.6 (4.4;6.7) | 0.026 |
| LH (mIU/mL)c | 2.6 (1.3;5.3) | 4.7 (3.6;6.7) | < 0.001 |
| Prolactin (ng/mL)c | 8.3 (6.6;12.5) | 12.2 (9.4;14.0) | 0.003 |
| Oestradiol (pg/mL)c | 24 (14;37) | 59 (47;68) | < 0.001 |
| Testosterone (pg/mL)c | 0.22 (0.13;0.30) | 0.24 (0.17;0.31) | 0.479 |
| Androstenedione (ng/mL)c | 1.45 (0.98;2.37) | 1.58 (1.19;2.04) | 0.825 |
| DHEAS (µg/mL)c | 2.16 (1.53;3.06) | 2.16 (1.80;2.74) | 0.963 |
| SHBG (nmol/L)c | 73.2 (55.1;104.0) | 81.2 (61.1;104.5) | 0.397 |
| AMH (ng/mL)c | 2.57 (1.57;6.18) | 3.08 (2.24;4.07) | 0.960 |
Variables are expressed as anumbers (frequencies) or.cmedian (IQR)
Multiple nominations are possible for bFHA causes