Table 2.
Using Cox proportional hazard analyses for postsurgical RFS in development set
| Parameter | Univariable cox proportional hazard analysis | Multivariable cox proportional hazard analysis | ||||
|---|---|---|---|---|---|---|
| Regression coefficient | Hazard ratio | P value | Regression coefficient | Hazard ratio | P value | |
| Age | − 0.016 | 0.984(0.963,1.006) | 0.157 | |||
| Male sex | 0.063 | 1.065(0.705,1.608) | 0.766 | |||
| Tumor size(cm) | 0.349 | 1.417(1.222,1.644) | < 0.001 | − 0.248 | 1.277(1.098,1.495) | 0.002 |
| Dominant location | 0.165 | |||||
| Head | − 0.105 | 0.901(0.566,1.434) | 0.659 | |||
| Body | − 0.721 | 0.486(0.227,1.042) | 0.486 | |||
| Tail | 1 | 1[reference] | – | |||
| Tumor density in AP | 0.747 | |||||
| Hyperdense | 1 | 1[reference] | – | |||
| Isodensel | 0.301 | 1.351(0.407,4.491) | 0.623 | |||
| Hypodense | 0.200 | 1.020(0.373,2.787) | 0.969 | |||
| Tumor density in PVP | < 0.001 | − 0.940 | 0.598(0.424,0.844) | 0.003 | ||
| Hyperdense | 1 | 1[reference] | – | |||
| Isodensel | 0.407 | 1.503(0.714,3.163) | 0.283 | |||
| Hypodense | 1.141 | 3.129(1.526,6.416) | 0.002 | |||
| Tumor necrosis (Yes/No) | 0.104 | 1.110(0.451,2.733) | 0.821 | |||
| Peripancreatic infiltration (Yes/No) | − 1.489 | 0.226(0.116,0.438) | < 0.001 | 1.423 | 4.151(2.077,8.298) | < 0.001 |
| Contact to SMV or PV | − 0.228 | 0.431(0.451,1.405) | 0.431 | |||
| Suspicious metastatic lymph node | − 1.089 | 0.336(0.223,0.507) | < 0.001 | 0.940 | 2.561(1.653,3.967) | < 0.001 |
| Cancer antigen 19–9 | 0.000 | 1(1,1) | 0.009 | 0.000 | 1(1,1) | 0.430 |
| Bilirubin | 0.003 | 1.003(1.001,1.005) | 0.011 | |||
| Neutrophils/Lymphocytes ratio | 0.138 | 1.148(1.066,1.237) | < 0.001 | 0.105 | 1.111(1.016,1.215) | 0.020 |
| Platelets/Lymphocytes ratio | 0.000 | 1(1,1) | 0.835 | |||
| C-reactive protein(mg/L) | − 0.042 | 0.959(0.905,1.016) | 0.159 | |||
Data in parentheses are 95% confidence intervals
AP Arterial phase, PV portal vein, PVP portal venous phase, SMV superior mesenteric vein