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. Author manuscript; available in PMC: 2022 Jul 4.
Published in final edited form as: Rev Recent Clin Trials. 2017;12(2):111–123. doi: 10.2174/1574887112666170321121250

Fig. (2).

Fig. (2).

An important element of therapeutic development is the use of small trials that are underpinned with a deep understanding of tumor molecular pathology that guides trial development, along with a strong sense of the therapeutics’ safety profile.